ART PRP Plus



The ART PRP Plus has an integrated filter system for the concentration of proteins from Platelet Poor Plasma (PPP) to create a fluid rich in growth factors.

During this process, water and salt ions are pushed out while the beneficial proteins are retained and concentrated.

The PPP can be passed multiple times from syringe to syringe through the filter until the desired volume is obtained.

This ultra-filtration enriches the concentration of most proteins like VEGF, PDGF, TGF-Beta, FGF, Alpha-2 Macroglobulin (A2M), Interleukin-1 receptor antagonist protein (IRAP) and Fibrinogen..

Platelet Rich Plasma (PRP) is an Indirect Therapy



  • Derived from peripheral blood
  • NO Stem Cells in whole blood
  • Joints: PRP accelerates healing of acute and chronic musculoskeletal injuries by promoting cellular differentiation, tissue healing and recruitment of Mesenchymal Stem Cells (MSCs) and other repair-related cells
  • Skin: recruits fibroblasts and MSCs to the skin, stimulating the formation of collagen and promoting healing
  • Hair: The PRP recruits fibroblasts and MSCs to the scalp, stimulating the hair follicles and promoting hair regrowth
  • Wound Healing: expedites the would healing process by promoting proteins, growth factors and cytokines to restore the structure and function of the damaged tissue

Benefits of PRP Therapy



  • Minimally invasive, out patient procedure with short recovery time
  • Accelerates tissue healing and repairs damaged tissue using the patients own cells
  • Platelets and growth factors enhance the healing of soft tissue
  • Alternative option to surgery and high dose steroid injections
  • Adaptable techniques to achieve a patient specific outcome to improve quality of life

The Process

Collect - Concentrate - Deliver



Collect:
  • 54 - 60 cc of autologous blood
Concentrate:

Centrifuge & Extract the Buffy Coat

  • One 15 minute spin at 3200 RPM
  • Stacks into 3 layers
  • Pull Buffy Coat in 3 simple steps
  • Yield 3 - 5 cc of Buffy Coat
  • Yield 3 - 5 cc of General Fluid Concentrate from 25 - 30 cc of PPP
  • Customizable 6 - 10 cc final volume for injection after filtration of PPP
  • The cells and proteins are accurately isolated and concentrated at point of care
  • Concentrate ~ 70% platelets from peripheral blood
Deliver:
  • Inject final desired volume at the site of injury to ensure the concentrated cells are placed precisely where optimal healing can occur in the safest way possible
 

Growth Factors and Proteins available after filtration



 
 
 

Features



  • Single use sterile device designed to collect, process and deliver at the point of care
  • Separation of cells by centrifugation is simple and yields the best cell numbers and provides the best cell viability
  • Easy separation of fluid fractions (e.g. PRP, PPP)
  • The systems recovers the greatest percentage of nucleated and progenitor cells
  • GFC: more proteins available in BMC than PRP
  • Efficient concentration yields ultra-low hematocrit with only 1 spin
  • Adjustable flow valve simplifies the process of separating and combining cells, growth factors and other proteins
  • Multiple ports to accommodate the fewest sterile breaks
  • Thumb wheel allows for precise recovery of the targeted cell layer and recovers high yields of platelets and growth factors
  • Built-in back chamber allows for the convenience of adding PPP to the PRP or BMC if more volume is desired for injection
  • Integrated filter system for the ultra-filtration of proteins from the PPP
  • Manual manipulation is the critical feature that produces optimal recovery and a customized final product

Have Questions?



If you are interested for more details please get in touch with Paola Jiménez, Product Manager & Global Sales at paola@rxbio.co.

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